Prevalence of Cholera among Admitted Patients of Federal Medical Centre (FMC), Keffi, Nasarawa State, Nigeria

A Retrospective Observational Study

Authors

  • Collins Emmanuel Akpan
    Department of Mathematics, Federal University of Lafia, Nigeria
  • Yusuf Emmanuel Atanyi
    Department of Mathematics, Federal University of Lafia, Nigeria
  • Imam Akeyede
    Department of Statistics, Federal University of Lafia, Nigeria
  • Olukayode Orole
    Department of Microbiology, Federal University of Lafia, Nigeria
  • Peter Ogiri Agbo
    Department of Pharmacy, Federal Medical Centre Keffi, Nigeria

Keywords:

Cholera , Epidemiology , Case Fatality Rate , Morbidity , Mortality , Public Health

Abstract

This study evaluates the epidemiological trends, morbidity, and mortality patterns of cholera among patients at Federal Medical Centre (FMC) Keffi from 2021 to 2025. The findings revealed fluctuating case incidence with peaks in 2022 and resurgence in 2025, alongside a persistently high case fatality rate. Age-specific outcomes demonstrated a U-shaped mortality pattern affecting both pediatric and geriatric populations, while sex-based outcomes showed no significant difference. These findings align with national trends in Nigeria, where cholera remains endemic due to poor water, sanitation, and hygiene (WASH) conditions. The study emphasizes the need for improved surveillance, early diagnosis, and targeted interventions.

Dimensions

Abubakar, A. S., Ehidiamhen, F. E., & Okolo, M. O. (2026). COVID-19 in suspected cases at Federal Medical Centre Keffi: A retrospective analysis of clinical features and age-specific vulnerabilities (2021–2025). Journal of Tropical Medicine & Infectious Disease, 11(2), 45–58.

Austin, P. C. (2017). A tutorial on multilevel survival analysis: Methods, models and applications. Statistics in Medicine, 36(20), 3226–3246.

Dowdy, D., & D’Souza, G. (2020). What is test positivity and why does it matter? Johns Hopkins Coronavirus Resource Center.

Ehidiamhen, F. E., Abubakar, A. S., & Usman, T. (2025). Trends and determinants of mortality among children in Nigeria: A teaching hospital perspective. Open Journal of Pathology, 15(4), 152–168.

Elimian, K. (2024). Enablers and barriers to implementing cholera interventions in Nigeria. Health Policy and Planning.

Guerra-Silveira, F., & Abad-Franch, F. (2013). Sex bias in infectious disease epidemiology: Patterns and processes. PLoS ONE, 8(4), e63806.

Godwin M., Collins E. A & Moses Y. E. Akpan (2026). Modeling Cholera Dynamics with Vaccination and Asymptotic Transmission. A Mathematical framework for outbreak control. Fulafia Journal of Science and Technology. 10(1):103–109. https://doi.org/10.62050/fjst2026.v10n1.720

Hosmer, D. W., Lemeshow, S., & Sturdivant, R. X. (2013). Applied logistic regression (3rd ed.). Wiley Series in Probability and Statistics.

Kelly, H., Peck, A. J., Morens, D. M., & Taubenberger, J. K. (2011). The case fatality ratio: A critical metric for assessing the severity of infectious disease outbreaks. Bulletin of the World Health Organization, 89, 536–541.

Klein, S. L., & Flanagan, K. L. (2016). Sex differences in immune responses. Nature Reviews Immunology, 16(10), 626–638.

Lancet Nigeria Commission. (2022). Population health outcomes in Nigeria: A comparison with regional and global standards. The Lancet, 399(10330), 1140–1213.

Mike-Ogburia, (2025). Cholera in Nigeria: Trends and public health responses. Nigerian Medical Journal.

National Population Commission (NPC) [Nigeria]. (2022). Nigeria Demographic and Health Survey (NDHS) 2021–2022. NPC and ICF.

O’Driscoll, M., Ribeiro Dos Santos, G., Wang, L., Cummings, D. A. T., Azman, A. S., Paireau, J., Fontanet, A., Cauchemez, S., & Salje, H. (2021). Age-specific mortality and immunity patterns of SARS-CoV-2. Nature, 590(7844), 140–145.

Ogunniyi, T. J., Muoneke, A. P., Nimo, F., & Olorunfemi, O. A. (2025). Cholera in Nigeria: A five-decade review of outbreak dynamics. Journal of Health, Population and Nutrition.

Okolo, M. O., Abubakar, A. S., & Usman, T. (2022). Seroprevalence and burden of hepatitis E viral infection among pregnant women in Central Nigeria: A study from FMC Keffi. Frontiers in Medicine, 9, 888218.

Simonsen, L., Clarke, M. J., Williamson, G. D., Stroup, D. F., Arden, N. H., & Schonberger, L. B. (1998). Pandemic versus epidemic influenza mortality: A pattern of age-specific death rates. American Journal of Epidemiology, 147(5), 443–450.

Sperandei, S. (2014). Understanding logistic regression analysis. Biochemia Medica, 24(1), 12–18.

Spychalski, P., Błażyńska-Spychalska, A., & Kobiela, J. (2020). Is case fatality rate an appropriate index to represent the status of an epidemic? Journal of Infection and Public Health, 13(10), 1411–1413.

Takahashi, T., Ellingson, M. K., Wong, P., Israelow, B., Lucas, C., Klein, J., Silva, J., Mao, T., Oh, J. E., Tokuyama, M., Lu, P., Venkataraman, A., Park, A., Liu, F., Meir, A., Sun, J., Wang, E. Y., Casanovas-Massana, A., Wyllie, A. L., ... Iwasaki, A. (2020). Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature, 588(7837), 315–320.

World Health Organization. (2020a). Estimating mortality from COVID-19: Scientific brief. who.int

World Health Organization. (2020b). Public health criteria to adjust public health and social measures in the context of COVID-19. Interim guidance.

cover

Published

2026-04-29

How to Cite

Prevalence of Cholera among Admitted Patients of Federal Medical Centre (FMC), Keffi, Nasarawa State, Nigeria: A Retrospective Observational Study. (2026). Lafia Journal of Scientific and Industrial Research, 4(1), 233-242. https://doi.org/10.62050/ljsir2026.v4n1.828

Issue

Volume 4, Issue 1 (April, 2026), Lafia Journal of Scientific and Industrial Research (LJSIR)

Section

Physical Sciences
Copyright & Licensing

Copyright (c) 2026 Collins Emmanuel Akpan, Yusuf Emmanuel Atanyi , Imam Akeyede, Olukayode Orole , Peter Ogiri Agbo (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

How to Cite

Prevalence of Cholera among Admitted Patients of Federal Medical Centre (FMC), Keffi, Nasarawa State, Nigeria: A Retrospective Observational Study. (2026). Lafia Journal of Scientific and Industrial Research, 4(1), 233-242. https://doi.org/10.62050/ljsir2026.v4n1.828

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